Does anyone know of an app that can change what

[smaug]

Does anyone know of an app that can change what the hardware buttons do on a per application basis? It would be great to have the up and down buttons change to page up and page down in certain apps but remain up and down in others. If not, this would be a great 3rd party idea!

[Kamalot]

I too am interested in this kind of software. Each application I use has different needs.

[Phoenix]

You should really check out StrokeIt.
It can be a bit time consuming to assign gestures to all your programs, but once you're done you wont ever look back. No need to move your hand all the way over to the edge of the screen, just use your pen to control everything.